#15 Ohio State (+2) over Michigan - There's no way Michigan keeps this game close, right? The Buckeyes will travel to Ann Arbor and likely continue to worsen the mood among John Beilein and his underachieving Wolverines, who are 1-4 ATS at home this season. The Buckeyes are coming off one of their worst losses in recent memory (a 23 point drubbing to Wisconsin), but with the 30th ranked defense in the country, they should be able to control Michigan's inconsistent offense.
Wake Forest (-3.5) over Xavier - In what could turn into one of the better home-and-home series in the college game, two former Skip Prosser-coached teams will square off in season one of a 10 year contract. The Musketeers are 1-4 away from the Cintas Center this season, and struggle to neutralize their opponent's star players (Lazar Hayward, Jacob Pullen, and Gordon Hayward all scored at or above their PPG averages in wins over XU this season). Expect the Demon Deacons Al-Farouq Aminu to continue that trend this afternoon.
#7 Duke (-11) over #21 Clemson - Don't think Coach K forgot about the 27 point loss his team took on the chin last season at Littlejohn. Both teams come in undefeated since losing in the ACC/Big 10 Challenge, but it's the Blue Devils who are really playing hot. They boast a scoring margin of 26 points, a nation's best offensive efficiency rating of 123, and have converted on 43.3 percent of their three point attempts. The Tigers will need to force at or above their average of 20 turnovers per game to keep this contest interesting.